Functional roles of low calorie sweeteners on gut function

A C Meyer-Gerspach; B Wölnerhanssen; C Beglinger

doi:10.1016/j.physbeh.2016.01.045

Functional roles of low calorie sweeteners on gut function

Physiol Behav. 2016 Oct 1;164(Pt B):479-481. doi: 10.1016/j.physbeh.2016.01.045. Epub 2016 Feb 6.

Authors

A C Meyer-Gerspach¹, B Wölnerhanssen², C Beglinger³

Affiliations

¹ Department of Biomedicine, University Hospital Basel, and University of Basel, Switzerland.
² Department of Research, St. Claraspital, Basel, Switzerland; Department of Biomedicine, University Hospital Basel, and University of Basel, Switzerland.
³ Department of Research, St. Claraspital, Basel, Switzerland. Electronic address: beglinger@tmr.ch.

PMID: 26861179
DOI: 10.1016/j.physbeh.2016.01.045

Abstract

This short review summarizes the effects of low calorie sweeteners (fructose, non-nutritive low calorie sweeteners) on gut functions focusing on the gut sweet taste receptor system. The effects of these molecules on secretion of gut peptides associated with glycemic homeostasis and appetite regulation is reviewed as well as effects on gastric emptying and glucose absorption.

Keywords: Fructose; Glucose; Low calorie sweeteners; Sweet taste.

Publication types

Review

MeSH terms

Animals
Gastric Mucosa / metabolism*
Humans
Non-Nutritive Sweeteners / chemistry*
Receptors, G-Protein-Coupled / metabolism*
Taste / physiology*

Substances

Non-Nutritive Sweeteners
Receptors, G-Protein-Coupled