Characterization of a new HLA-A allele, HLA-A*02:07:08, by cloning and sequencing

Int J Immunogenet. 2016 Apr;43(2):109-10. doi: 10.1111/iji.12249. Epub 2016 Feb 9.

Abstract

In this report, we present a novel HLA-A*02:07 allele, HLA-A*02:07:08. HLA-A*02:07:08 was identified in an individual of Han ethnicity in Hunan province, southern China. Following polymerase chain reaction-sequence-based typing (PCR-SBT), this new allele was further confirmed by cloning and sequencing. HLA-A*02:07:08 differs from HLA-A*02:07:01 by a single synonymous C to T substitution at nucleotide position 131 in exon 3.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles*
  • Asian People
  • China
  • Cloning, Molecular*
  • Exons
  • HLA-A Antigens / genetics*
  • Humans
  • Sequence Analysis, DNA*

Substances

  • HLA-A Antigens

Associated data

  • GENBANK/KP404443