Molecular detection of CTX-M-15-type β-lactamases in Escherichia coli strains from Senegal

M L Dia; B Ngom; R Diagne; R Ka; S Lo; M F Cisse; G Arlet; A I Sow

doi:10.1016/j.nmni.2015.11.009

Molecular detection of CTX-M-15-type β-lactamases in Escherichia coli strains from Senegal

New Microbes New Infect. 2015 Nov 23:9:45-6. doi: 10.1016/j.nmni.2015.11.009. eCollection 2016 Jan.

Authors

M L Dia¹, B Ngom¹, R Diagne¹, R Ka¹, S Lo², M F Cisse³, G Arlet⁴, A I Sow¹

Affiliations

¹ Bacteriology Laboratory, Fann University Hospital, Dakar, Senegal.
² Bacteriology Laboratory, Regional Hospital of Saint-Louis, Dakar, Senegal.
³ Bacteriology Laboratory, Albert Royer Children's Hospital, Dakar, Senegal.
⁴ Bacteriology Laboratory, Pierre et Marie Curie University, Paris, France.

Abstract

We aimed to detect the extended-spectrum β-lactamases (ESBLs) secreted by clinical strains of Escherichia coli at Fann University Hospital in Dakar and to characterize them molecularly. We identified 32 isolates producing ESBLs. The CTX-M-15 gene was the most frequently detected ESBL gene, detected in 90.63% of the isolates studied.

Keywords: Escherichia coli; Senegal; extended-spectrum β-lactamases; genes; molecular characterization.