Coronary patients with high plasma omentin are at a higher cardiovascular risk

Christoph H Saely; Andreas Leiherer; Axel Muendlein; Alexander Vonbank; Philipp Rein; Kathrin Geiger; Cornelia Malin; Heinz Drexel

doi:10.1016/j.dib.2015.11.065

Coronary patients with high plasma omentin are at a higher cardiovascular risk

Data Brief. 2015 Dec 11:6:158-61. doi: 10.1016/j.dib.2015.11.065. eCollection 2016 Mar.

Authors

Christoph H Saely¹, Andreas Leiherer², Axel Muendlein², Alexander Vonbank¹, Philipp Rein¹, Kathrin Geiger², Cornelia Malin³, Heinz Drexel⁴

Affiliations

¹ Department of Medicine and Cardiology, Academic Teaching Hospital Feldkirch, Feldkirch, Austria; Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria; Private University of the Principality of Liechtenstein, Triesen, Liechtenstein.
² Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria; Private University of the Principality of Liechtenstein, Triesen, Liechtenstein.
³ Department of Medicine and Cardiology, Academic Teaching Hospital Feldkirch, Feldkirch, Austria; Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria.
⁴ Department of Medicine and Cardiology, Academic Teaching Hospital Feldkirch, Feldkirch, Austria; Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria; Private University of the Principality of Liechtenstein, Triesen, Liechtenstein; Drexel College University of Medicine, Philadelphia, PA, USA.

Abstract

The adipokine omentin, also known as intelectin, is a secretory protein, expressed in visceral adipose tissue and is highly abundant in plasma. It is involved in the development of chronic inflammatory diseases, but nothing is known about its impact on the cardiovascular event risk. Here, plasma omentin was measured in 295 patients undergoing coronary angiography for the evaluation of established or suspected stable coronary artery disease (CAD). Patients were separated according to the median plasma omentin concentrations into a high and low omentin group and cardiovascular events occurring during a period of 3.5 years have been recorded. We observed that patients within the high omentin group had significantly more cardiovascular events than patients in the low omentin group. This was true even if using different study endpoints. This article describes data related to a research article titled "High Plasma Omentin Predicts Cardiovascular Events Independently From the Presence and Extent of Angiographically Determined Atherosclerosis" (Saely et al., 2015) [1].

Keywords: Adipokine; Adipose tissue; Atherosclerosis; Coronary angiography; Coronary artery disease; Omentin; Prognostic factor; Prospective cohort study.