Targeting NOTCH1 in T-ALL: Starving the dragon

Cell Cycle. 2016;15(4):483-4. doi: 10.1080/15384101.2015.1128191. Epub 2016 Feb 11.
No abstract available

Publication types

  • Editorial

MeSH terms

  • Cell Cycle / genetics
  • Gene Expression Regulation, Leukemic / genetics
  • Glycolysis / genetics
  • Humans
  • Molecular Targeted Therapy*
  • PTEN Phosphohydrolase / genetics*
  • PTEN Phosphohydrolase / metabolism
  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / genetics
  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / pathology
  • Receptor, Notch1 / antagonists & inhibitors
  • Receptor, Notch1 / biosynthesis*
  • Receptor, Notch1 / genetics
  • Signal Transduction

Substances

  • NOTCH1 protein, human
  • Receptor, Notch1
  • PTEN Phosphohydrolase
  • PTEN protein, human