Short-Term Improvement in Physical Activity and Body Composition After Supervised Exercise Training Program in Idiopathic Pulmonary Fibrosis

Baruch Vainshelboim; Benjamin Daniel Fox; Mordechai Reuven Kramer; Shimon Izhakian; Evgeni Gershman; Jose Oliveira

doi:10.1016/j.apmr.2016.01.018

Short-Term Improvement in Physical Activity and Body Composition After Supervised Exercise Training Program in Idiopathic Pulmonary Fibrosis

Arch Phys Med Rehabil. 2016 May;97(5):788-97. doi: 10.1016/j.apmr.2016.01.018. Epub 2016 Feb 8.

Authors

Baruch Vainshelboim¹, Benjamin Daniel Fox², Mordechai Reuven Kramer², Shimon Izhakian³, Evgeni Gershman³, Jose Oliveira⁴

Affiliations

¹ Pulmonary Institute, Rabin Medical Center, Beilinson Hospital, Petach Tikva, Israel; Research Center in Physical Activity, Health and Leisure (CIAFEL), Faculty of Sport, University of Porto, Porto, Portugal. Electronic address: baruch.v1981@gmail.com.
² Pulmonary Institute, Rabin Medical Center, Beilinson Hospital, Petach Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
³ Pulmonary Institute, Rabin Medical Center, Beilinson Hospital, Petach Tikva, Israel.
⁴ Research Center in Physical Activity, Health and Leisure (CIAFEL), Faculty of Sport, University of Porto, Porto, Portugal.

PMID: 26869288
DOI: 10.1016/j.apmr.2016.01.018

Abstract

Objective: To examine the effect of participating in a 12-week supervised exercise training (ET) program on physical activity and body composition in patients with idiopathic pulmonary fibrosis (IPF).

Design: Randomized controlled trial assessing physical activity and body composition at baseline, after 12-week intervention, and at 11 months follow-up.

Setting: Outpatient hospital.

Participants: Patients with IPF (N=34; mean age, 68±8y) recruited for this study; 32 patients completed the 12-week intervention (ET group: n=15; control group: n=17) and 28 patients (14 in each group) reassessed at 11-month follow-up from baseline.

Interventions: Participation in a 12-week supervised ET program or regular medical treatment.

Main outcome measures: Changes in physical activity levels as measured by the International Physical Activity Questionnaire.

Results: After the 12-week intervention, physical activity levels were significantly increased in the ET group whereas the control group showed a trend toward deterioration (median difference between the groups, 2164MET-min/wk [interquartile range, 1576MET-min/wk]; MET = metabolic equivalent; P<.001). Body composition was also significantly improved in the ET group, whereas the control group showed an opposite trend. At 11-month follow-up, no significant differences were observed between the 2 groups in all variables. The ET group lost most of the achieved improvements in the outcomes and returned to near baseline levels, whereas the control group showed a trend toward worsened outcomes.

Conclusions: Physical activity and body composition in patients with IPF were improved after a 12-week supervised ET program, although the benefits were not sustained at 11-month follow-up. These results may support the efficacy of participation in supervised ET to improve physical activity and body composition in patients with IPF; however, maintenance strategies are warranted to preserve the improved outcomes.

Trial registration: ClinicalTrials.gov NCT01499745.

Keywords: Exercise; Rehabilitation; Waist circumference.

Publication types

Randomized Controlled Trial

MeSH terms

Aged
Body Composition / physiology*
Exercise / physiology*
Exercise Therapy / methods*
Female
Follow-Up Studies
Humans
Idiopathic Pulmonary Fibrosis / physiopathology
Idiopathic Pulmonary Fibrosis / rehabilitation*
Male
Middle Aged
Treatment Outcome

Associated data

ClinicalTrials.gov/NCT01499745