Zika virus and the risk of imported infection in returned travelers: Implications for clinical care

Travel Med Infect Dis. 2016 Jan-Feb;14(1):13-15. doi: 10.1016/j.tmaid.2016.01.008. Epub 2016 Jan 27.


Since late 2015, an unprecedented outbreak of Zika virus is spreading quickly across Southern America. The large size of the current outbreak in The Americas will also result in an increase in Zika virus infections among travelers returning from endemic areas. We report five cases of imported Zika virus infection to The Netherlands. Although the clinical course is usually mild, establishing the diagnosis is important, mainly because of the association with congenital microcephaly and the possibility of sexual transmission.

Keywords: Case series; Microcephaly; Sexual transmission; Travel; Zika virus.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Americas
  • Disease Outbreaks / prevention & control
  • Female
  • Humans
  • Male
  • Microcephaly / virology
  • Middle Aged
  • Netherlands
  • Risk Factors
  • Sexually Transmitted Diseases, Viral / diagnosis
  • Sexually Transmitted Diseases, Viral / transmission*
  • South America / epidemiology
  • Travel*
  • United States
  • Zika Virus / genetics
  • Zika Virus / isolation & purification
  • Zika Virus Infection / diagnosis
  • Zika Virus Infection / epidemiology*
  • Zika Virus Infection / transmission*
  • Zika Virus Infection / virology