[Differential diagnosis of Graves' orbitopathy. Case report]

Orv Hetil. 2016 Feb 21;157(8):310-5. doi: 10.1556/650.2016.30381.
[Article in Hungarian]

Abstract

Graves' orbitopathy is the extrathyroidal manifestation of Graves' disease, which is the most common cause of exophthalmos. As eye symptoms usually coincide with the development of thyrotoxicosis, the diagnosis of the disease is rarely difficult. The aim of the authors was to summarize the differential diagnosis of Graves' orbitopathy based on literature review and presentation of their own four problematic cases on this topic. They conclude that symptoms similar to endocrine orbitopathy are present in other disorders. Endocrinologists need to be aware of these other conditions to avoid treatment failures.

Keywords: Graves’ orbitopathy; IgG4-asszociált betegség; IgG4-related disease; endokrin orbitopathia; idiopathic inflammatory orbitopathy; idiopathiás inflammatorikus orbitopathia; myasthenia gravis; occularis lymphoma; ocular lymphoma.

Publication types

  • Case Reports
  • English Abstract
  • Review

MeSH terms

  • Adrenal Cortex Hormones / administration & dosage
  • Adrenal Cortex Hormones / therapeutic use*
  • Adult
  • Aged
  • Diagnosis, Differential
  • Diplopia / etiology
  • Eye Neoplasms / complications
  • Eye Neoplasms / diagnosis*
  • Female
  • Graves Ophthalmopathy / drug therapy
  • Graves Ophthalmopathy / etiology*
  • Humans
  • Hypergammaglobulinemia / complications
  • Hypergammaglobulinemia / diagnosis*
  • Immunoglobulin G / blood*
  • Inflammation / complications
  • Inflammation / diagnosis*
  • Leukemia, Lymphocytic, Chronic, B-Cell / complications
  • Leukemia, Lymphocytic, Chronic, B-Cell / diagnosis*
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Orbit / pathology*
  • Orbital Diseases / diagnosis
  • Thyrotoxicosis / complications
  • Thyrotoxicosis / diagnosis*
  • Treatment Outcome

Substances

  • Adrenal Cortex Hormones
  • Immunoglobulin G