Cannabis-induced psychosis associated with high potency "wax dabs"

Schizophr Res. 2016 Apr;172(1-3):211-2. doi: 10.1016/j.schres.2016.01.056. Epub 2016 Feb 11.


With mounting evidence that the risk of cannabis-induced psychosis may be related to both dose and potency of tetrahydrocannbinol (THC), increasing reports of psychosis associated with cannabinoids containing greater amounts of THC are anticipated. We report two cases of emergent psychosis after using a concentrated THC extract known as cannabis "wax," "oil," or "dabs" raising serious concerns about its psychotic liability. Although "dabbing" with cannabis wax is becoming increasingly popular in the US for both recreational and "medicinal" intentions, our cases raise serious concerns about its psychotic liability and highlight the importance of understanding this risk by physicians recommending cannabinoids for purported medicinal purposes.

Keywords: Cannabis; Cannabis oil; Cannabis wax; Cannabis-induced psychosis, catatonia; Marijuana; Tetrahydrocannabinol.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Cannabis / toxicity*
  • Diagnosis, Differential
  • Dronabinol / toxicity*
  • Follow-Up Studies
  • Humans
  • Illicit Drugs / toxicity*
  • Male
  • Marijuana Abuse / complications*
  • Marijuana Abuse / therapy
  • Plant Extracts / toxicity*
  • Psychoses, Substance-Induced / diagnosis
  • Psychoses, Substance-Induced / etiology*
  • Psychoses, Substance-Induced / therapy


  • Illicit Drugs
  • Plant Extracts
  • Dronabinol