Completion Rate and Side-Effect Profile of Three-Month Isoniazid and Rifapentine Treatment for Latent Tuberculosis Infection in an Urban County Jail

Open Forum Infect Dis. 2016 Jan 6;3(1):ofv220. doi: 10.1093/ofid/ofv220. eCollection 2016 Jan.

Abstract

In an urban jail population, 3 months of isoniazid and rifapentine (3HP) was associated with an 85% latent tuberculosis infection treatment completion rate compared with 18% in a standard 9-month isoniazid treatment group. Among the 91 patients who started 3HP therapy, there were 2 treatment discontinuations from adverse drug reactions.

Keywords: correctional healthcare; prevention; tuberculosis.