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. 2016 Jun;13(3):295-8.
doi: 10.1071/SH15192.

Prevalence of Human herpesvirus-8 Among HIV-infected Patients, Intravenous Drug Users and the General Population in Iran

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Prevalence of Human herpesvirus-8 Among HIV-infected Patients, Intravenous Drug Users and the General Population in Iran

Rezvan Kakavand-Ghalehnoei et al. Sex Health. .

Abstract

Studies looking at the frequency of human herpesvirus-8 (HHV-8) among Iranian blood donors have produced conflicting results. The aim of this study was to investigate the prevalence of HHV-8 DNA by using polymerase chain reaction methods among 168 healthy individuals, 60 intravenous drug users and 100 HIV-infected patients from Iran. The prevalence of HHV-8 was significantly higher among intravenous drug users (13.3%) compared with the general population (3.6%; P=0.017). The HHV-8 genome was mostly detected among intravenous drug users who displayed high-risk sexual behaviours. Moreover, the HHV-8 genome was also detected in 8% of HIV-infected patients. The present study findings support the likelihood that the transmission of HHV-8 is via a sexual route in the Iranian population.

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