Epigenetic Modulators and the New Immunotherapies

N Engl J Med. 2016 Feb 18;374(7):684-6. doi: 10.1056/NEJMcibr1514673.
No abstract available

MeSH terms

  • Animals
  • Antimetabolites, Antineoplastic / pharmacology
  • Azacitidine / pharmacology
  • DNA (Cytosine-5-)-Methyltransferases / antagonists & inhibitors*
  • DNA Methylation / drug effects*
  • Enzyme Inhibitors / pharmacology
  • Epigenesis, Genetic*
  • Gene Expression / drug effects
  • Humans
  • Immunotherapy*
  • Mice
  • Neoplasms / genetics
  • Neoplasms / immunology*

Substances

  • Antimetabolites, Antineoplastic
  • Enzyme Inhibitors
  • DNA (Cytosine-5-)-Methyltransferases
  • Azacitidine