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, 31 (1), 62-71

Brief Report: Renal Replacement Therapy in Korea, 2010

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Brief Report: Renal Replacement Therapy in Korea, 2010

Dong Chan Jin et al. Kidney Res Clin Pract.

Abstract

The Korean Society of Nephrology (KSN) launched the official End-Stage Renal Disease (ESRD) Patient Registry in 1985 and the Internet online registry program was opened in 2001. The ESRD Registry Committee of KSN has collected data on dialysis therapy in Korea through the online registry program in the KSN Internet website. The increasing number of elderly people and diabetic patients in Korea has resulted in a very rapid increase in the number of ESRD patients. The total number of ESRD patients was 58,860 (hemodialysis [HD], 39,509; peritoneal dialysis [PD], 7309; and functioning kidney transplant [KT], 12,042). The prevalence of ESRD was 1144.4 patients per million population (PMP), and the proportion of renal replacement therapy was HD, 67.1%; PD, 12.4%; and KT, 20.5%. The number of new ESRD patients in 2010 was 9335 (HD, 7204; PD, 867; and KT, 1264; the incidence rate was 181.5 PMP). The primary causes of ESRD were diabetic nephropathy (45.2%), hypertensive nephrosclerosis (19.2%), and chronic glomerulonephritis (11.3%). The mean urea reduction ratio was 67.9% in male HD patients and 73.9% in female HD patients. The mean Kt/V was 1.394 in male patients and 1.659 in female patients. Five-year survival rates of male and female dialysis patients were 64.9% and 67.3%, respectively.

Keywords: End stage renal disease; Hemodialysis; Korea; Peritoneal dialysis.

Figures

Figure 1
Figure 1
Prevalence and incidence of end stage renal replacement therapy in Korea. The number of patient with renal replacement therapy at the end of each year (a); point prevalence of renal replacement therapy (b); patients starting renal replacement therapy in each year (c); three major causes of end-stage renal disease (d). CGN, chronic glomerulonephritis; DM, diabetic nephropathy; HD, hemodialysis; HTN, hypertensive nephrosclerosis; KT, kidney transplantation; PD, peritoneal dialysis; PMP, patient numbers per million population; RRT, renal replacement therapy.
Figure 2
Figure 2
Renal replacement therapy modalities. Proportion of renal replacement modalities. Annual prevalence and incidence in 2010 (a); number of hemodialysis centers and hemodialysis machines (b); number of hemodialysis patients and hemodialysis patients per hemodialysis machine (c); percent distribution of hemodialysis patients according to dialysis center classification (d); regional distribution of dialysis patients in Korea (e).
Figure 3
Figure 3
Dialysis patient demographics. Gender ratio of hemodialysis and peritoneal dialysis patients according to year (a); age distribution of dialysis patients according to dialysis modalities (b); age distribution of dialysis patients according to age. Note that the peak age was shifted to old age (c); age distribution of dialysis patients according to underlying diseases (d); duration of maintenance hemodialysis and peritoneal dialysis. Percent of estimated patient number according to year (e); duration of dialysis maintenance in diabetic and non-diabetic patients (f); distribution of body mass index in hemodialysis and peritoneal dialysis patients (g); distribution of mean blood pressure in hemodialysis and peritoneal dialysis patients. Blood pressure was higher in hemodialysis patients than in peritoneal dialysis patients (h); systolic and diastolic blood pressure with pulse pressure in hemodialysis and peritoneal dialysis patients (i).
Figure 3
Figure 3
Dialysis patient demographics. Gender ratio of hemodialysis and peritoneal dialysis patients according to year (a); age distribution of dialysis patients according to dialysis modalities (b); age distribution of dialysis patients according to age. Note that the peak age was shifted to old age (c); age distribution of dialysis patients according to underlying diseases (d); duration of maintenance hemodialysis and peritoneal dialysis. Percent of estimated patient number according to year (e); duration of dialysis maintenance in diabetic and non-diabetic patients (f); distribution of body mass index in hemodialysis and peritoneal dialysis patients (g); distribution of mean blood pressure in hemodialysis and peritoneal dialysis patients. Blood pressure was higher in hemodialysis patients than in peritoneal dialysis patients (h); systolic and diastolic blood pressure with pulse pressure in hemodialysis and peritoneal dialysis patients (i).
Figure 4
Figure 4
Characteristics of erythropoietin, hemodialysis, and peritoneal dialysis therapy. Changes in hematocrit (%) in dialysis patients: hemodialysis vs. peritoneal dialysis (a); percent distribution of erythropoietin doses prescribed for hemodialysis and peritoneal dialysis patients (b); frequency of hemodialysis per week (c); current use of hemodialysis membrane, dialysis membrane reuse, and hemodiafiltration percentage in private clinics (d); distribution of the urea reduction ratio in hemodialysis patients (e); dialysis adequacy parameters (nPCR and Kt/V) in hemodialysis patients (f); dialysis adequacy parameters (Kt/V) in diabetic and non-diabetic hemodialysis patients (g); distribution of peritoneal dialysis types and doses (percentage) (h).
Figure 4
Figure 4
Characteristics of erythropoietin, hemodialysis, and peritoneal dialysis therapy. Changes in hematocrit (%) in dialysis patients: hemodialysis vs. peritoneal dialysis (a); percent distribution of erythropoietin doses prescribed for hemodialysis and peritoneal dialysis patients (b); frequency of hemodialysis per week (c); current use of hemodialysis membrane, dialysis membrane reuse, and hemodiafiltration percentage in private clinics (d); distribution of the urea reduction ratio in hemodialysis patients (e); dialysis adequacy parameters (nPCR and Kt/V) in hemodialysis patients (f); dialysis adequacy parameters (Kt/V) in diabetic and non-diabetic hemodialysis patients (g); distribution of peritoneal dialysis types and doses (percentage) (h).
Figure 5
Figure 5
Morbidities, causes of death, and survival rates of dialysis patients. Comparison of causes of death in hemodialysis vs. peritoneal dialysis patients in 2001–2010 (a); overall survival of registered dialysis patient since 2001 (male: n=22,257; female: n=16,520) (b); HD and PD dialysis patient survival since 2001 (HD: n=31,354, PD: n=7423) (c); overall diabetic and non-diabetic dialysis patient survival since 2001 (Non-DM: n=18,786; DM: n=19,991) (d). DM, diabetic nephropathy; HD, hemodialysis; PD, peritoneal dialysis.
Figure 6
Figure 6
Annual number of kidney transplantations (KT) in Korea (including data from the Korean Network for Organ Sharing). *Surviving KT waiting patient number at the end of each year.

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