Use of Platelet Preparations in Facial Rejuvenation and Wound Healing Remains Unproven

Aesthetic Plast Surg. 2016 Apr;40(2):329-30. doi: 10.1007/s00266-016-0622-0. Epub 2016 Feb 18.


There is growing interest in the use of platelet derivatives in facial aesthetic surgery and wound healing. Sclafani et al. have concluded from their review of the literature that the vast majority of studies show a significant and measurable effect on facial aesthetic outcomes with the use of these platelet preparations. We suggest that an alternative review of the same literature may well have produced a different set of conclusions.

Level of evidence v: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors

Keywords: Facial esthetics; Growth factors; Platelet gel; Platelet-rich fibrin; Platelet-rich fibrin matrix; Platelet-rich plasma; Platelets; Wound healing.

Publication types

  • Letter
  • Comment

MeSH terms

  • Animals
  • Blood Platelets*
  • Cosmetic Techniques*
  • Face*
  • Humans
  • Platelet-Rich Plasma*
  • Rejuvenation*
  • Wound Healing*