Cultural adaptation of a cognitive-behavioural intervention to improve adherence to antiretroviral therapy among people living with HIV/AIDS in Zimbabwe: Nzira Itsva

J Health Psychol. 2017 Sep;22(10):1265-1276. doi: 10.1177/1359105315626783. Epub 2016 Feb 18.


Few evidence-based interventions to improve adherence to antiretroviral therapy have been adapted for use in Africa. We selected, culturally adapted and tested the feasibility of a cognitive-behavioural intervention for adherence and for delivery in a clinic setting in Harare, Zimbabwe. The feasibility of the intervention was evaluated using a mixed-methods assessment, including ratings of provider fidelity of intervention delivery, and qualitative assessments of feasibility using individual semi-structured interviews with counsellors (n=4) and patients (n=15). The intervention was feasible and acceptable when administered to 42 patients and resulted in improved self-reported adherence in a subset of 15 patients who were followed up after 6months.

Keywords: AIDS; HIV; adherence; cognitive-behavioural therapy; culture; intervention.

MeSH terms

  • Acquired Immunodeficiency Syndrome / drug therapy
  • Adult
  • Aged
  • Antirheumatic Agents / therapeutic use*
  • Cognitive Behavioral Therapy / methods*
  • Culturally Competent Care / methods*
  • Female
  • HIV Infections / drug therapy*
  • Humans
  • Male
  • Medication Adherence / ethnology*
  • Middle Aged
  • Outcome and Process Assessment, Health Care*
  • Young Adult
  • Zimbabwe / ethnology


  • Antirheumatic Agents