Recurrent IgA Nephropathy After Kidney Transplantation

Transplantation. 2016 Sep;100(9):1827-32. doi: 10.1097/TP.0000000000001093.

Abstract

Large numbers of patients with end-stage kidney disease caused by IgA nephropathy are transplanted every year, and each of these patients faces the risk of recurrence in their kidney graft. We review the epidemiology, diagnosis, and outcomes of recurrent IgA nephropathy. Mechanistic insights, therapeutic options, and knowledge gaps are reviewed, and we discuss future options to better understand and manage this disorder.

Publication types

  • Review

MeSH terms

  • Biopsy
  • Glomerulonephritis, IGA / complications*
  • Glomerulonephritis, IGA / diagnosis
  • Glomerulonephritis, IGA / immunology
  • Glomerulonephritis, IGA / mortality
  • Humans
  • Kidney / immunology
  • Kidney / pathology
  • Kidney / surgery*
  • Kidney Failure, Chronic / diagnosis
  • Kidney Failure, Chronic / etiology
  • Kidney Failure, Chronic / mortality
  • Kidney Failure, Chronic / surgery*
  • Kidney Transplantation / adverse effects*
  • Kidney Transplantation / mortality
  • Predictive Value of Tests
  • Recurrence
  • Retreatment
  • Risk Factors
  • Time Factors
  • Treatment Outcome