Mooren's ulcer: 30 years of follow-up

Arch Soc Esp Oftalmol. 2016 Jul;91(7):337-40. doi: 10.1016/j.oftal.2016.01.021. Epub 2016 Feb 17.
[Article in English, Spanish]

Abstract

Case report: A 33-year-old Caucasian female presented with epiphora, ocular pain, and foreign body sensation in both eyes for one month. Examination revealed bilateral peripheral corneal ulcers. The patient had been treated with immunomodulators, and she was treated in the left eye with peripheral semi-circular keratoplasty, penetrating keratoplasty, conjunctival-corneal-scleroplasty, buccal mucosal graft, tibial osteo-keratoprosthesis and finally, retinal detachment.

Discussion: Mooren's ulcer is an immunological corneal disease. This lesion must be treated initially with immunomodulators. Surgical treatment should be considered when a risk of corneal perforation is present, when the perforation appears, or under acute necrosis.

Keywords: Corneal perforation; Desprendimiento de retina; Immunosuppression; Inmunosupresión; Keratoplasty; Mooren's ulcer; Osteo-keratoprosthesis; Osteo-queratoprótesis; Perforación corneal; Queratoplastia; Retinal detachment; Vitrectomy; Vitrectomía; Úlcera de Mooren.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cataract Extraction
  • Combined Modality Therapy
  • Contact Lenses
  • Corneal Transplantation / methods*
  • Corneal Ulcer / drug therapy
  • Corneal Ulcer / immunology
  • Corneal Ulcer / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Keratoplasty, Penetrating
  • Mouth Mucosa / transplantation
  • Reoperation
  • Tibia / transplantation
  • Transplantation, Heterotopic
  • Vitrectomy

Substances

  • Immunosuppressive Agents