Guidelines of care for the management of acne vulgaris

J Am Acad Dermatol. 2016 May;74(5):945-73.e33. doi: 10.1016/j.jaad.2015.12.037. Epub 2016 Feb 17.


Acne is one of the most common disorders treated by dermatologists and other health care providers. While it most often affects adolescents, it is not uncommon in adults and can also be seen in children. This evidence-based guideline addresses important clinical questions that arise in its management. Issues from grading of acne to the topical and systemic management of the disease are reviewed. Suggestions on use are provided based on available evidence.

Keywords: Propionibacterium acnes; acne; acne management; acne vulgaris; amoxicillin; antiandrogens; azithromycin; benzoyl peroxide; clindamycin; contraceptive agents; diet and acne; doxycycline; erythromycin; grading and classification of acne; guidelines; hormonal therapy; isotretinoin; light therapies; microbiological and endocrine testing; oral corticosteroids; retinoids; salicylic; spironolactone; systemic therapies; tetracyclines; topical antibiotics; trimethoprim.

Publication types

  • Review

MeSH terms

  • Acne Vulgaris / diagnosis*
  • Acne Vulgaris / drug therapy*
  • Administration, Oral
  • Administration, Topical
  • Adolescent
  • Adult
  • Anti-Bacterial Agents / therapeutic use*
  • Dermatologic Agents / therapeutic use*
  • Evidence-Based Medicine
  • Female
  • Follow-Up Studies
  • Humans
  • Isotretinoin / therapeutic use
  • Male
  • Practice Guidelines as Topic*
  • Recurrence
  • Risk Assessment
  • Treatment Outcome
  • Young Adult


  • Anti-Bacterial Agents
  • Dermatologic Agents
  • Isotretinoin