Effects of indigo carmine intravenous injection on noninvasive and continuous total hemoglobin measurement with using the Revision L sensor

J Clin Monit Comput. 2017 Apr;31(2):485-486. doi: 10.1007/s10877-016-9850-8. Epub 2016 Feb 22.


The effects of intravenous injection of indigo carmine on noninvasive and continuous total hemoglobin (SpHb) measurement were retrospectively evaluated with the Revision L sensor. The subjects were 18 patients who underwent elective gynecologic surgery under general anesthesia. During surgery, 5 mL of 0.4 % indigo carmine was injected intravenously, and changes in SpHb concentrations between before and after the injection were evaluated. The mean age was 52.4 ± 12.8 years. Before injection, the median SpHb level was 10.1 (range, 6.8-13.4) g/dL. The results demonstrated no change in SpHb concentration between before and after indigo carmine injection as detected by the Revision L sensor. SpHb measurements as determined with the Revision L sensor were not affected, even after the intravenous injection of indigo carmine.

Keywords: CO-oximetry; Indigo carmine; Revision L; SpHb.

Publication types

  • Letter

MeSH terms

  • Adult
  • Aged
  • Anesthesia, General
  • Elective Surgical Procedures
  • Female
  • Gynecologic Surgical Procedures
  • Hemoglobinometry / instrumentation*
  • Hemoglobins / analysis*
  • Humans
  • Indigo Carmine*
  • Injections, Intravenous*
  • Middle Aged
  • Monitoring, Intraoperative / instrumentation*
  • Monitoring, Intraoperative / methods*
  • Oximetry / instrumentation*
  • Retrospective Studies


  • Hemoglobins
  • Indigo Carmine