Effects of Millimeter-Wave Electromagnetic Radiation on the Experimental Model of Migraine

Bull Exp Biol Med. 2016 Feb;160(4):425-8. doi: 10.1007/s10517-016-3187-7. Epub 2016 Feb 22.

Abstract

Effects of millimeter-wave electromagnetic radiation (40 GHz frequency, 0.01 mW power) on the spontaneous fi ring of convergent neurons of the spinal trigeminal nucleus and their responses to electrical stimulation of the dura mater were studied in neurophysiological experiments on rats. Irradiation of the area of cutaneous receptive fields of spinal trigeminal nucleus reversibly inhibited both spontaneous discharges and activity induced by electrical stimulation of the dura mater. The second and third exposures to electromagnetic radiation with an interval of 10 min were ineffective. These results suggest that suppression of neuronal excitability in the spinal trigeminal ganglion can be a mechanism of the anti-migraine effects of electromagnetic radiation observed in clinical practice.

Keywords: migraine; millimeter-wave electromagnetic radiation; neuronal activity; spinal trigeminal nucleus.

MeSH terms

  • Animals
  • Disease Models, Animal
  • Dura Mater / radiation effects*
  • Electric Stimulation / methods*
  • Electromagnetic Radiation*
  • Male
  • Migraine Disorders / therapy*
  • Neurons / radiation effects*
  • Rats
  • Rats, Wistar
  • Trigeminal Nucleus, Spinal / radiation effects*