Bone Marrow Synoptic Reporting for Hematologic Neoplasms: Guideline From the College of American Pathologists Pathology and Laboratory Quality Center

Arch Pathol Lab Med. 2016 Sep;140(9):932-49. doi: 10.5858/arpa.2015-0450-SA. Epub 2016 Feb 23.

Abstract

Context: -There is ample evidence from the solid tumor literature that synoptic reporting improves accuracy and completeness of relevant data. No evidence-based guidelines currently exist for synoptic reporting for bone marrow samples.

Objective: -To develop evidence-based recommendations to standardize the basic components of a synoptic report template for bone marrow samples.

Design: -The College of American Pathologists Pathology and Laboratory Quality Center convened a panel of experts in hematopathology to develop recommendations. A systematic evidence review was conducted to address 5 key questions. Recommendations were derived from strength of evidence, open comment feedback, and expert panel consensus.

Results: -Nine guideline statements were established to provide pathology laboratories with a framework by which to develop synoptic reporting templates for bone marrow samples. The guideline calls for specific data groups in the synoptic section of the pathology report; provides a list of evidence-based parameters for key, pertinent elements; and addresses ancillary testing.

Conclusion: -A framework for bone marrow synoptic reporting will improve completeness of the final report in a manner that is clear, succinct, and consistent among institutions.

Publication types

  • Consensus Development Conference
  • Practice Guideline
  • Systematic Review

MeSH terms

  • American Medical Association
  • Bone Marrow Examination / methods
  • Hematologic Neoplasms / diagnosis*
  • Humans
  • Laboratories / standards*
  • Pathologists
  • Pathology, Clinical / methods
  • Pathology, Clinical / organization & administration
  • Pathology, Clinical / standards*
  • Research Report / standards*
  • United States