[Disseminated tuberculosis revealing IgA nephropathy with nephrotic syndrome : A case report]

Abstract

A 27-year-old man without any medical history presented concomitantly a pulmonary and urinary tuberculosis and a nephrotic syndrome with hematuria and renal failure. The renal biopsy showed increased mesangial matrix, few focal segmental lesions, and IgA deposits confirming the diagnosis of IgA nephropathy. Nephrotic syndrome remission occurred quickly after antituberculous treatment. The association between tuberculosis and IgA nephropathy has been previously reported in 9 patients. Renal outcome was always favorable with antituberculous treatment. No relapse occurred, with a maximal follow-up of 42 months. Here, we discuss this singular association and previous similar cases.

Keywords: Glomerulonephritis; Glomérulopathie à IgA; IgA; Nephrotic syndrome; Syndrome néphrotique; Tuberculose; Tuberculosis.