The Timeline of Influenza Virus Shedding in Children and Adults in a Household Transmission Study of Influenza in Managua, Nicaragua

doi:10.1097/INF.0000000000001083

. 2016 May;35(5):583-6.

doi: 10.1097/INF.0000000000001083.

The Timeline of Influenza Virus Shedding in Children and Adults in a Household Transmission Study of Influenza in Managua, Nicaragua

Sophia Ng¹, Roger Lopez, Guillermina Kuan, Lionel Gresh, Angel Balmaseda, Eva Harris, Aubree Gordon

Affiliations

Affiliation

¹ From the *Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan; †Centro Nacional de Diagnóstico y Referencia, Ministry of Health, Managua, Nicaragua; ‡Centro de Salud Sócrates Flores Vivas Health Center, Ministry of Health, Managua, Nicaragua; §Sustainable Sciences Institute, Managua, Nicaragua; and ¶Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California.

PMID: 26910589
PMCID: PMC4829445
DOI: 10.1097/INF.0000000000001083

The Timeline of Influenza Virus Shedding in Children and Adults in a Household Transmission Study of Influenza in Managua, Nicaragua

Sophia Ng et al. Pediatr Infect Dis J. 2016 May.

. 2016 May;35(5):583-6.

doi: 10.1097/INF.0000000000001083.

Authors

Sophia Ng¹, Roger Lopez, Guillermina Kuan, Lionel Gresh, Angel Balmaseda, Eva Harris, Aubree Gordon

Affiliation

¹ From the *Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan; †Centro Nacional de Diagnóstico y Referencia, Ministry of Health, Managua, Nicaragua; ‡Centro de Salud Sócrates Flores Vivas Health Center, Ministry of Health, Managua, Nicaragua; §Sustainable Sciences Institute, Managua, Nicaragua; and ¶Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California.

PMID: 26910589
PMCID: PMC4829445
DOI: 10.1097/INF.0000000000001083

Abstract

In a household transmission study in Nicaragua, children under 6 years old had a longer duration of presymptomatic influenza virus shedding than adults. The duration of postsymptomatic influenza virus shedding was longest in children 0-5 years old, followed by children 6-15 years of age and adults.

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Conflict of interest statement

Conflict of Interest Statement

The authors declare no conflict of interest.

Figures

**Figure 1**
Persistence of viral shedding within 20 days of viral shedding onset

See this image and copyright information in PMC

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References

1. Suess T, Remschmidt C, Schink SB, et al. Comparison of Shedding Characteristics of Seasonal Influenza Virus (Sub)Types and Influenza A(H1N1)pdm09; Germany, 2007–2011. PLoS ONE. 2012;7(12):e51653. - PMC - PubMed
1. Loeb M, Singh PK, Fox J, et al. Longitudinal study of influenza molecular viral shedding in Hutterite communities. J Infect Dis. 2012;206(7):1078–1084. - PubMed
1. Lau LLH, Ip DKM, Nishiura H, et al. Heterogeneity in virus shedding among medically-attended influenza A virus infections. J Infect Dis. 2013 Feb;:jit034. - PMC - PubMed
1. Frank AL, Taber LH, Wells CR, Wells JM, Glezen WP, Paredes A. Patterns of shedding of myxoviruses and paramyxoviruses in children. J Infect Dis. 1981;144(5):433–441. - PubMed
1. Cowling BJ, Chan KH, Fang VJ, et al. Comparative Epidemiology of Pandemic and Seasonal Influenza A in Households. New England Journal of Medicine. 2010;362(23):2175–2184. - PMC - PubMed

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[1] Suess T, Remschmidt C, Schink SB, et al. Comparison of Shedding Characteristics of Seasonal Influenza Virus (Sub)Types and Influenza A(H1N1)pdm09; Germany, 2007–2011. PLoS ONE. 2012;7(12):e51653. - PMC - PubMed

[2] Suess T, Remschmidt C, Schink SB, et al. Comparison of Shedding Characteristics of Seasonal Influenza Virus (Sub)Types and Influenza A(H1N1)pdm09; Germany, 2007–2011. PLoS ONE. 2012;7(12):e51653. - PMC - PubMed

[3] Loeb M, Singh PK, Fox J, et al. Longitudinal study of influenza molecular viral shedding in Hutterite communities. J Infect Dis. 2012;206(7):1078–1084. - PubMed

[4] Loeb M, Singh PK, Fox J, et al. Longitudinal study of influenza molecular viral shedding in Hutterite communities. J Infect Dis. 2012;206(7):1078–1084. - PubMed

[5] Lau LLH, Ip DKM, Nishiura H, et al. Heterogeneity in virus shedding among medically-attended influenza A virus infections. J Infect Dis. 2013 Feb;:jit034. - PMC - PubMed

[6] Lau LLH, Ip DKM, Nishiura H, et al. Heterogeneity in virus shedding among medically-attended influenza A virus infections. J Infect Dis. 2013 Feb;:jit034. - PMC - PubMed

[7] Frank AL, Taber LH, Wells CR, Wells JM, Glezen WP, Paredes A. Patterns of shedding of myxoviruses and paramyxoviruses in children. J Infect Dis. 1981;144(5):433–441. - PubMed

[8] Frank AL, Taber LH, Wells CR, Wells JM, Glezen WP, Paredes A. Patterns of shedding of myxoviruses and paramyxoviruses in children. J Infect Dis. 1981;144(5):433–441. - PubMed

[9] Cowling BJ, Chan KH, Fang VJ, et al. Comparative Epidemiology of Pandemic and Seasonal Influenza A in Households. New England Journal of Medicine. 2010;362(23):2175–2184. - PMC - PubMed

[10] Cowling BJ, Chan KH, Fang VJ, et al. Comparative Epidemiology of Pandemic and Seasonal Influenza A in Households. New England Journal of Medicine. 2010;362(23):2175–2184. - PMC - PubMed

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The Timeline of Influenza Virus Shedding in Children and Adults in a Household Transmission Study of Influenza in Managua, Nicaragua

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The Timeline of Influenza Virus Shedding in Children and Adults in a Household Transmission Study of Influenza in Managua, Nicaragua

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