Metastatic Renal Cell Carcinoma in a Hepatic Hemangioma: A Case Report and Review of the Literature

Int J Surg Pathol. 2016 Sep;24(6):552-5. doi: 10.1177/1066896916634207. Epub 2016 Feb 24.


We report the case of 55-year-old female with biopsy-proven clear cell renal cell carcinoma with a suspicious lesion found in the liver who presented for right radical nephrectomy and partial hepatectomy. Histologic evaluation of the hepatic specimen demonstrated metastatic renal cell carcinoma within a hepatic hemangioma. Herein we provide a review of the literature for this uncommon scenario.

Keywords: hepatic hemangioma; renal cell carcinoma; tumor-to-tumor metastasis; vascular endothelial growth factor (VEGF).

Publication types

  • Case Reports
  • Review

MeSH terms

  • Carcinoma, Renal Cell / secondary*
  • Female
  • Hemangioma / pathology*
  • Humans
  • Kidney Neoplasms / pathology*
  • Liver Neoplasms / pathology*
  • Liver Neoplasms / secondary*
  • Middle Aged