Mid-term results of leaflet augmentation in severe tricuspid functional tethering

Eur J Cardiothorac Surg. 2016 Sep;50(3):504-8. doi: 10.1093/ejcts/ezw039. Epub 2016 Feb 27.

Abstract

Objectives: Functional tricuspid regurgitation (FTR) is usually managed surgically using various types of annuloplasty. FTR has been reported to recur in up to 45% of patients, with severe leaflet tethering being an important risk factor for recurrence. The aim of this study is to report the clinical and echocardiographic mid-term results after leaflet augmentation in patients with FTR due to severe leaflet tethering.

Methods: From May 2008 to July 2014, 22 patients were found to have a severe FTR with a tethering height of at least 8 mm; all of them underwent leaflet augmentation: the anterior and part of the posterior leaflet were detached from the anterior annulus; a patch of fresh autologous pericardium was used to generously fill the gap between the anterior annulus and the detached leaflet. A 5/0 Pronova suture locked at every step was used to avoid any purse string effect. In 2 patients, the septal leaflet also needed to be augmented using a comparable technique. In all but one (annular calcification) patient, a semi-rigid ring annuloplasty was added. The mean age was 67.1 ± 13.7 years; it was a redo procedure in 12 cases (54.5%), 11 patients (50%) had right ventricle failure and 3 (23.1%) had renal failure.

Results: The median follow-up was 2.1 ± 1.9 years. Thirty-day and 4-year survival averaged at 81.1 ± 8.5 and 71.6 ± 9.8%, respectively. At 4 years, 84 ± 10.6% of the survivors were in NYHA class I or II and only 2 patients had a TR of ≥2 with a global freedom from TR ≥2 of 85.7 ± 13.2%. There was no reintervention.

Conclusions: Tricuspid leaflet augmentation combined with annuloplasty is feasible and leads to excellent clinical and echocardiographical mid-term results even in the presence of severe leaflet tethering and right ventricular failure.

Keywords: Tricuspid valve regurgitation.

MeSH terms

  • Aged
  • Belgium / epidemiology
  • Cardiac Valve Annuloplasty / methods*
  • Echocardiography / methods*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Recurrence
  • Retrospective Studies
  • Risk Factors
  • Severity of Illness Index
  • Survival Rate / trends
  • Time Factors
  • Tricuspid Valve / diagnostic imaging
  • Tricuspid Valve / surgery*
  • Tricuspid Valve Insufficiency / diagnosis
  • Tricuspid Valve Insufficiency / mortality
  • Tricuspid Valve Insufficiency / surgery*