Endoscopic Radiofrequency Ablation-Assisted Resection of Juvenile Nasopharyngeal Angiofibroma: Comparison with Traditional Endoscopic Technique

Otolaryngol Head Neck Surg. 2016 Jun;154(6):1145-8. doi: 10.1177/0194599816630942. Epub 2016 Mar 1.

Abstract

Objectives: To evaluate the feasibility of radiofrequency surgical instrumentation for endoscopic resection of juvenile nasopharyngeal angiofibroma (JNA) and to test the hypothesis that endoscopic radiofrequency ablation-assisted (RFA) resection will have superior intraoperative and/or postoperative outcomes as compared with traditional endoscopic (TE) resection techniques.

Study design: Case series with chart review.

Setting: Two tertiary care pediatric hospitals.

Subjects and methods: Twenty-nine pediatric patients who underwent endoscopic transnasal resection of JNA from January 2000 to December 2014.

Results: Twenty-nine patients underwent RFA (n = 13) or TE (n = 16) JNA resection over the 15-year study period. Mean patient age was not statistically different between the 2 groups (P = .41); neither was their University of Pittsburgh Medical Center classification stage (P = .79). All patients underwent preoperative embolization. Mean operative times were not statistically different (P = .29). Mean intraoperative blood loss and the need for a transfusion were also not statistically different (P = .27 and .47, respectively). Length of hospital stay was not statistically different (P = .46). Recurrence rates did not differ between groups (P = .99) over a mean follow-up period of 2.3 years.

Conclusion: There were no significant differences between RFA and TE resection in intraoperative or postoperative outcome parameters.

Keywords: endoscopic resection; epistaxis; juvenile nasopharyngeal angiofibroma; radiofrequency ablation; skull base tumor.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Angiofibroma / surgery*
  • Catheter Ablation / methods*
  • Endoscopy / methods*
  • Feasibility Studies
  • Female
  • Humans
  • Male
  • Nasopharyngeal Neoplasms / surgery*
  • Radio Waves
  • Retrospective Studies
  • Treatment Outcome