Riyadh Mother and Baby Multicenter Cohort Study: The Cohort Profile

PLoS One. 2016 Mar 3;11(3):e0150297. doi: 10.1371/journal.pone.0150297. eCollection 2016.

Abstract

Objectives: To assess the effects of non-communicable diseases, such as diabetes, hypertension and obesity, on the mother and the infant.

Methods: A multicentre cohort study was conducted in three hospitals in the city of Riyadh in Saudi Arabia. All Saudi women and their babies who delivered in participating hospitals were eligible for recruitment. Data on socio-demographic characteristics in addition to the maternal and neonatal outcomes of pregnancy were collected. The cohort demographic profile was recorded and the prevalence of maternal conditions including gestational diabetes, pre-gestational diabetes, hypertensive disorders in pregnancy and obesity were estimated.

Findings: The total number of women who delivered in participating hospitals during the study period was 16,012 of which 14,568 women participated in the study. The mean age of the participants was 29 ± 5.9 years and over 40% were university graduates. Most of the participants were housewives, 70% were high or middle income and 22% were exposed to secondhand smoke. Of the total cohort, 24% were married to a first cousin. More than 68% of the participants were either overweight or obese. The preterm delivery rate was 9%, while 1.5% of the deliveries were postdate. The stillbirth rate was 13/1000 live birth. The prevalence of gestational diabetes was 24% and that of pre-gestational diabetes was 4.3%. The preeclampsia prevalence was 1.1%. The labour induction rate was 15.5% and the cesarean section rate was 25%.

Conclusion: Pregnant women in Saudi Arabia have a unique demographic profile. The prevalence of obesity and diabetes in pregnancy are among the highest in the world.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cohort Studies
  • Diabetes, Gestational / epidemiology*
  • Female
  • Humans
  • Obesity / epidemiology*
  • Pre-Eclampsia / epidemiology
  • Pregnancy
  • Prevalence
  • Saudi Arabia / epidemiology
  • Stillbirth / epidemiology
  • Young Adult

Grants and funding

RAHMA study is supported by King Abdullah International Medical Research Center grant number RC11/062, King Fahad Medical City Research Center grant number KFMC-IRF-013-017, and the Deanship of Postgraduate Education and Research at the College of Medicine, King Saud University. The funders had no role in study design, data collection, data analysis, decision to publish or preparation of the manuscript.