New technologies in drug metabolism and toxicity screening: organ-to-organ interaction

Expert Opin Drug Metab Toxicol. 2016 May;12(5):475-7. doi: 10.1517/17425255.2016.1162292. Epub 2016 Mar 21.

Authors

Abhinav Bhushan¹, Nicole J Martucci², O Berk Usta³, Martin L Yarmush^{3

4}

Affiliations

¹ a Department of Biomedical Engineering , Illinois Institute of Technology , Chicago , IL , USA.
² b Department of Biomedical Engineering , Binghamton University , Binghamton , NY , USA.
³ c Center for Engineering in Medicine, Harvard Medical School , Massachusetts General Hospital , Boston , MA , USA.
⁴ d Department of Biomedical Engineering , Rutgers University , Piscataway , NJ , USA.

No abstract available

Keywords: Drug metabolism; drug toxicity; humanized mice; induced pluripotent cells; microphysiological; organs on chips; systems.

MeSH terms

Animals
Computer Simulation
Drug Design*
Drug Evaluation, Preclinical / methods
Drug-Related Side Effects and Adverse Reactions / prevention & control
Humans
Pharmaceutical Preparations / metabolism*
Toxicity Tests / methods*

Substances

Pharmaceutical Preparations

Grants and funding