New technologies in drug metabolism and toxicity screening: organ-to-organ interaction

Expert Opin Drug Metab Toxicol. 2016 May;12(5):475-7. doi: 10.1517/17425255.2016.1162292. Epub 2016 Mar 21.
No abstract available

Keywords: Drug metabolism; drug toxicity; humanized mice; induced pluripotent cells; microphysiological; organs on chips; systems.

MeSH terms

  • Animals
  • Computer Simulation
  • Drug Design*
  • Drug Evaluation, Preclinical / methods
  • Drug-Related Side Effects and Adverse Reactions / prevention & control
  • Humans
  • Pharmaceutical Preparations / metabolism*
  • Toxicity Tests / methods*

Substances

  • Pharmaceutical Preparations