Phytochemical profiling of five medicinally active constituents across 14 Eutrema species

Fitoterapia. 2016 Apr;110:83-8. doi: 10.1016/j.fitote.2016.03.001. Epub 2016 Mar 3.


Wasabi or Japanese horseradish (Eutrema japonicum) is both a traditional condiment and a medicinally important plant with diverse uses. Its medicinally active constituents appear to include five isothiocyanates, but their spatial variations in naturally occurring congeners are unknown. Thus, in this study we measured concentrations of these five active constituents in 20 populations of 14 species of Eutrema and one related species, Yinshania sinuata. Three to five of these constituents were detected in each of the examined species, at concentrations that varied greatly between sampled species and populations of the same species. However, two species, Eutrema tenue and Eutrema deltoideum, had higher total concentrations of the five isothiocyanates and substantially higher concentrations of one or two, than the widely cultivated E. japonicum. Thus, both of these species could be important wild resources for artificial cultivation, in addition to the currently widely cultivated E. japonicum.

Keywords: Eutrema; Isothiocyanate; Phytochemical constituent.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brassicaceae / chemistry*
  • Brassicaceae / classification
  • China
  • Chromatography, High Pressure Liquid
  • Isothiocyanates / chemistry*
  • Isothiocyanates / isolation & purification
  • Phytochemicals / chemistry*
  • Phytochemicals / isolation & purification
  • Plants, Medicinal / chemistry
  • Plants, Medicinal / classification


  • Isothiocyanates
  • Phytochemicals
  • isothiocyanic acid