Re-refinement of 4g4a: room-temperature X-ray diffraction study of cisplatin and its binding to His15 of HEWL after 14 months chemical exposure in the presence of DMSO

Simon W M Tanley; Antoine M M Schreurs; Loes M J Kroon-Batenburg; John R Helliwell

doi:10.1107/S2053230X16000856

Re-refinement of 4g4a: room-temperature X-ray diffraction study of cisplatin and its binding to His15 of HEWL after 14 months chemical exposure in the presence of DMSO

Acta Crystallogr F Struct Biol Commun. 2016 Mar;72(Pt 3):253-4. doi: 10.1107/S2053230X16000856. Epub 2016 Feb 19.

Authors

Simon W M Tanley¹, Antoine M M Schreurs², Loes M J Kroon-Batenburg², John R Helliwell¹

Affiliations

¹ School of Chemistry, Faculty of Engineering and Physical Sciences, University of Manchester, Brunswick Street, Manchester M13 9PL, England.
² Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.

Abstract

A re-refinement of 4g4a, the room-temperature X-ray diffraction study of cisplatin and its binding to His15 of HEWL after 14 months chemical exposure in the presence of DMSO is published as an addendum to Tanley et al. [(2012), Acta Cryst. F68, 1300-1306]. This example illustrates the benefits of sharing raw diffraction images, as well as structure factors and molecular coordinates, as the diffraction resolution of the study is now much improved at 1.70 Å.

Keywords: addendum; cisplatin; histidine; improved diffraction resolution; raw diffraction images.; re-refinement.

Publication types

Published Erratum
Research Support, Non-U.S. Gov't