MR Imaging-Guided Attenuation Correction of PET Data in PET/MR Imaging

David Izquierdo-Garcia; Ciprian Catana

doi:10.1016/j.cpet.2015.10.002

MR Imaging-Guided Attenuation Correction of PET Data in PET/MR Imaging

PET Clin. 2016 Apr;11(2):129-49. doi: 10.1016/j.cpet.2015.10.002. Epub 2016 Jan 26.

Authors

David Izquierdo-Garcia¹, Ciprian Catana²

Affiliations

¹ Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Charlestown 02129, MA, USA. Electronic address: davidizq@nmr.mgh.harvard.edu.
² Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Charlestown 02129, MA, USA.

Abstract

Attenuation correction (AC) is one of the most important challenges in the recently introduced combined PET/magnetic resonance (MR) scanners. PET/MR AC (MR-AC) approaches aim to develop methods that allow accurate estimation of the linear attenuation coefficients of the tissues and other components located in the PET field of view. MR-AC methods can be divided into 3 categories: segmentation, atlas, and PET based. This review provides a comprehensive list of the state-of-the-art MR-AC approaches and their pros and cons. The main sources of artifacts are presented. Finally, this review discusses the current status of MR-AC approaches for clinical applications.

Keywords: Artifacts; Atlas; Attenuation correction; Body truncation; MR-AC; PET/MR imaging; Segmentation; Template.

Publication types

Review

MeSH terms

Artifacts
Humans
Image Enhancement / methods
Magnetic Resonance Imaging / methods*
Multimodal Imaging / methods*
Positron-Emission Tomography / methods*

Grants and funding

R01 EB014894/EB/NIBIB NIH HHS/United States