Occult invasive aspergillosis infection following multivisceral transplantation

C S Rutter; L M Sharkey; R Gao; C Pither; A Ibrahim; D A Enoch; A J Butler; S J Middleton

doi:10.1016/j.idcr.2014.06.005

Occult invasive aspergillosis infection following multivisceral transplantation

IDCases. 2014 Jul 10;1(3):53-4. doi: 10.1016/j.idcr.2014.06.005. eCollection 2014.

Authors

C S Rutter¹, L M Sharkey¹, R Gao¹, C Pither¹, A Ibrahim², D A Enoch³, A J Butler⁴, S J Middleton¹

Affiliations

¹ Department of Gastroenterology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK.
² Department of Histopathology and Cytology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK.
³ Clinical Microbiology and Public Health Laboratory (Public Health England), Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK.
⁴ Department of Transplant Surgery, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK.

Abstract

Patients undergoing multivisceral transplantation are particularly susceptible to post-operative infections due to immunosuppression and the inclusion of bowel in the transplanted graft. These patients typically receive broad-spectrum antimicrobial and antifungal agents as prophylaxis and treatment. However, evidence for this is limited due to the small number of patients undergoing the procedure. We present a case of occult disseminated invasive aspergillosis infection in a patient who underwent multivisceral transplantation.

Keywords: Galactomannan; Invasive aspergillosis; Moulds; Multivisceral transplant.

Publication types

Case Reports