Consequential considerations when mapping tRNA fragments

BMC Bioinformatics. 2016 Mar 10;17:123. doi: 10.1186/s12859-016-0921-0.

Abstract

We examine several of the choices that went into the design of tDRmapper, a recently reported tool for identifying transfer RNA (tRNA) fragments in deep sequencing data, evaluate them in the context of currently available knowledge, and discuss their potential impact on the output that the tool generates.

MeSH terms

  • Databases, Nucleic Acid*
  • High-Throughput Nucleotide Sequencing / methods*
  • Molecular Sequence Annotation*
  • RNA, Transfer / chemistry
  • RNA, Transfer / genetics*

Substances

  • RNA, Transfer