Hemophagocytic lymphohistiocytosis in leprosy

Lepr Rev. 2015 Dec;86(4):403-6.


A patient from Southeast Asia was diagnosed with systemic lupus erythematosus. One year later, she experienced exacerbation of skin lesions and was diagnosed with erythema nodosum leprosum. Upon treatment, the patient developed hemophagocytic lymphohistiocytosis with multi-organ failure and died from invasive fungal infection. Hemophagocytic lymphohistiocytosis has to our knowledge, not previously been reported in leprosy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Leprosy / complications*
  • Lymphohistiocytosis, Hemophagocytic / etiology*