Genome Sequences of Five Clinical Isolates of Klebsiella pneumoniae

L Letti Lopez; Brigida Rusconi; Heidi Gildersleeve; Chao Qi; Milena McLaughlin; Marc H Scheetz; J Seshu; Mark Eppinger

doi:10.1128/genomeA.00040-16

Genome Sequences of Five Clinical Isolates of Klebsiella pneumoniae

Genome Announc. 2016 Mar 10;4(2):e00040-16. doi: 10.1128/genomeA.00040-16.

Authors

L Letti Lopez¹, Brigida Rusconi¹, Heidi Gildersleeve¹, Chao Qi², Milena McLaughlin³, Marc H Scheetz³, J Seshu¹, Mark Eppinger⁴

Affiliations

¹ South Texas Center for Emerging Infectious Diseases, Center for Excellence in Infection Genomics and Department of Biology, The University of Texas at San Antonio, San Antonio, Texas, USA.
² Northwestern University Feinberg School of Medicine, Evanston, Illinois, USA.
³ Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy, Downers Grove, Illinois, USA Department of Pharmacy, Northwestern Memorial Hospital, Chicago, Illinois, USA.
⁴ South Texas Center for Emerging Infectious Diseases, Center for Excellence in Infection Genomics and Department of Biology, The University of Texas at San Antonio, San Antonio, Texas, USA mark.eppinger@utsa.edu.

Abstract

Klebsiella pneumoniae is a nosocomial pathogen of emerging importance and displays resistance to broad-spectrum antibiotics, such as carbapenems. Here, we report the genome sequences of five clinical K. pneumoniae isolates, four of which are carbapenem resistant. Carbapenem resistance is conferred by hydrolyzing class A β-lactamases found adjacent to transposases.

Abstract

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