A Case of Persistent and Possibly Treatment Resistant Pharyngeal Gonorrhea

Sex Transm Dis. 2016 Apr;43(4):258-9. doi: 10.1097/OLQ.0000000000000430.

Abstract

An HIV-negative man with pharyngeal gonorrhea had a positive test-of-cure (nucleic acid amplification test) result 7 days after treatment with ceftriaxone/azithromycin. Neisseria gonorrhoeae Multi-Antigen Sequencing Type 1407 and mosaic pen A (XXXIV) gene were identified in the test-of-cure specimen, and culture was negative. Retreatment with ceftriaxone 500 mg intramuscularly plus azithromycin 2 g orally yielded a negative test-of-cure result.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Asymptomatic Diseases
  • Azithromycin / therapeutic use*
  • Ceftriaxone / therapeutic use*
  • Gonorrhea / drug therapy*
  • Humans
  • Injections, Intramuscular
  • Male
  • Neisseria gonorrhoeae / genetics
  • Neisseria gonorrhoeae / immunology*
  • Nucleic Acid Amplification Techniques
  • Pharynx / microbiology
  • Sexually Transmitted Diseases / drug therapy*
  • Treatment Outcome
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • Ceftriaxone
  • Azithromycin