Dose comparison of classical 2-plane DSA and 3D rotational angiography for the assessment of intracranial aneurysms

Neuroradiology. 2016 Jul;58(7):673-8. doi: 10.1007/s00234-016-1671-4. Epub 2016 Mar 12.


Introduction: The purpose of this experimental phantom study was to compare radiation doses imparted to patients undergoing classical two-plane digital subtraction angiography (2-plane DSA) and 3D rotational angiography in interventional neuroradiology.

Methods: Thermoluminescence dosimeter (TLD) measurements were performed at an anthropomorphic phantom using a digital interventional angiography system. Two-plane DSA included posterior/anterior (PA) and lateral (LAT) projections (frame-rate, 7.6 frames (PA) and 9.8 frames (LAT) for a scan time of approximately 8 s; image intensifier 27 cm (PA) and 25 cm (LAT)). For 3D rotational angiography, 122 images were acquired from one single image run with the imaging system rotating 240° around the phantom's head (image intensifier 37 cm).

Results: Effective dose was 0.4 mSv for 2-plane DSA compared to 0.1 mSv for 3D rotational angiography. Organ doses were approximately two to five times higher for classical 2-plane technique compared to the 3D rotational angiography, respectively: brain (11.4 vs. 2.4 mSv), eye lens (4.5 vs.1 mSv), salivary glands (7 vs. 1,7 mSv), oral mucosa (2.7 vs.0.9 mSv), thyroid (0.5 vs. 0.2 mSv), thymus (0.2 vs. 0.05 mSv), bone marrow within imaged region (1 vs. 0.2 mSv), oesophagus (0.07 vs. 0.03 mSv), endotracheal system (2.6 vs. 0.7 mSv) and skeletal components in the imaged region (0.7 vs. 0.2 mSv).

Conclusion: Three-dimensional rotational angiography clearly reduces radiation doses compared to the classical 2-plane technique. Replacement of additional 2-plane DSA projections with 3D rotational angiography will lead to a remarkable decrease in patient radiation dose, without loss of image quality. Thus, we recommend routine application of 3D rotational angiography, in particular for diagnostic assessment of aneurysm morphology.

Keywords: 2-plane DSA; 3D rotational angiography; Dose measurement; Effective dose; Experimental phantom study.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Angiography, Digital Subtraction / instrumentation
  • Angiography, Digital Subtraction / methods*
  • Cerebral Angiography / instrumentation
  • Cerebral Angiography / methods*
  • Computed Tomography Angiography / instrumentation
  • Computed Tomography Angiography / methods*
  • Female
  • Humans
  • Imaging, Three-Dimensional / methods*
  • Intracranial Aneurysm / diagnostic imaging*
  • Male
  • Phantoms, Imaging
  • Radiation Dosage*
  • Radiation Exposure / analysis*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Thermoluminescent Dosimetry