Abstract
A rapid-response fluorescent probe ACDM was developed for the selective and sensitive detection of human albumin (HA) via binding onto a non-drug binding site. ACDM was successfully used to detect trace HA in various biological samples including diluted plasma and cell culture supernatants.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Binding Sites
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Chemistry Techniques, Analytical / methods*
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Chromatography, High Pressure Liquid
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Fluorescent Dyes / chemistry*
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Furans / chemistry
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Hep G2 Cells
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Humans
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Molecular Dynamics Simulation
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Protein Structure, Tertiary
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Serum Albumin / analysis*
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Serum Albumin / chemistry
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Tandem Mass Spectrometry
Substances
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Fluorescent Dyes
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Furans
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Serum Albumin
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furan