Tracheal replacement

J Thorac Dis. 2016 Mar;8(Suppl 2):S186-96. doi: 10.3978/j.issn.2072-1439.2016.01.85.


Non-malignant and malignant obstruction of the tracheal airway causes significant morbidity and mortality. With increased use of artificial airways, benign and iatrogenic complications are increasing. A tracheal stenosis that is less than 5 cm in length can be resected with end-to-end anastomosis. Longer tracheal lesions can be treated in a palliative way by placement of a stent to secure airway lumen patency. The management of tracheal defects is an evolving field. Tracheal transplantation and tracheal regeneration may bring major treatment advances to cases with long-segment tracheal involvement. This review examines the current possibilities and future prospects in the area of tracheal transplantation and regeneration.

Keywords: Trachea; regeneration; revascularization; transplant.

Publication types

  • Review