Does valproic acid affect tumor growth and improve survival in glioblastomas?

CNS Oncol. 2016;5(2):51-3. doi: 10.2217/cns-2016-0004. Epub 2016 Mar 17.

Authors

Roberta Rudà¹, Alessia Pellerino¹, Riccardo Soffietti¹

Affiliation

¹ Department of Neuro-Oncology, University & City of Health and Science Hospital, Via Cherasco 15, 10126, Turin, Italy.

No abstract available

Keywords: clinical studies; glioblastomas; gliomas; preclinical studies; seizures; tumor growth; valproic acid.

Publication types

Editorial

MeSH terms

Anticonvulsants / therapeutic use*
Antineoplastic Agents, Alkylating / therapeutic use
Brain Neoplasms / complications
Brain Neoplasms / drug therapy*
Brain Neoplasms / pathology
Cell Differentiation / drug effects
Cell Proliferation / drug effects
Combined Modality Therapy
Dacarbazine / analogs & derivatives
Dacarbazine / therapeutic use
Glioblastoma / complications
Glioblastoma / drug therapy*
Glioblastoma / pathology
Histone Deacetylase Inhibitors / therapeutic use*
Humans
Seizures / drug therapy*
Seizures / etiology
Temozolomide
Valproic Acid / therapeutic use*

Substances

Anticonvulsants
Antineoplastic Agents, Alkylating
Histone Deacetylase Inhibitors
Valproic Acid
Dacarbazine
Temozolomide