Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 12 (3), e1005452

Cooperation and Conflict in the Plant Immune System


Cooperation and Conflict in the Plant Immune System

Eunyoung Chae et al. PLoS Pathog.

Conflict of interest statement

The authors have declared that no competing interests exist.


Fig 1
Fig 1. Hypothetical phenotypic space determined by trade-offs between growth and immunity.
Common, reasonably fit genotypes are in black; genotypes that could potentially be created by crosses or mutations are in grey and orange. Green are genotypes closest to the Pareto front (grey line), which defines optimality among existing genotypes. The blue/yellow area represents forbidden phenotypic space, i.e., genotypes that die, always succumb to pathogens, or are infertile. The Pareto front can shift in response to a certain pathogen pressure or to abiotic challenge.

Similar articles

See all similar articles

Cited by 9 PubMed Central articles

See all "Cited by" articles


    1. Sinapidou E, Williams K, Nott L, Bahkt S, Tor M, et al. (2004) Two TIR:NB:LRR genes are required to specify resistance to Peronospora parasitica isolate Cala2 in Arabidopsis. Plant J 38: 898–909. - PubMed
    1. Cesari S, Kanzaki H, Fujiwara T, Bernoux M, Chalvon V, et al. (2014) The NB-LRR proteins RGA4 and RGA5 interact functionally and physically to confer disease resistance. EMBO J 33: 1941–1959. 10.15252/embj.201487923 - DOI - PMC - PubMed
    1. Williams SJ, Sohn KH, Wan L, Bernoux M, Sarris PF, et al. (2014) Structural basis for assembly and function of a heterodimeric plant immune receptor. Science 344: 299–303. 10.1126/science.1247357 - DOI - PubMed
    1. Sarris PF, Duxbury Z, Huh SU, Ma Y, Segonzac C, et al. (2015) A plant immune receptor detects pathogen effectors that target WRKY transcription factors. Cell 161: 1089–1100. 10.1016/j.cell.2015.04.024 - DOI - PubMed
    1. Le Roux C, Huet G, Jauneau A, Camborde L, Tremousaygue D, et al. (2015) A receptor pair with an integrated decoy converts pathogen disabling of transcription factors to immunity. Cell 161: 1074–1088. 10.1016/j.cell.2015.04.025 - DOI - PubMed

Publication types

Grant support

Our work on plant immunity is funded by ERC Advanced Grant IMMUNEMESIS, a grant from the Gordon and Betty Moore Foundation, and by the Max Planck Society. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.