Platelet-rich Plasma as a Novel Treatment for Lichen Planopillaris

Dermatol Ther. 2016 Jul;29(4):233-5. doi: 10.1111/dth.12343. Epub 2016 Mar 14.

Abstract

Treatment of lichen planopillaris (LPP) remains a significant challenge due to the irreversible damage inflicted on hair follicles combined with the low efficacy of existing treatments. We hypothesized that growth factors released by the use of platelet-rich plasma (PRP) may arrest the development of LPP. To test our hypothesis, we treated an LPP patient that has failed previous treatments with a new PRP regimen. Following PRP treatment and six months follow-up, the patient experienced complete regression of itching and hair shedding. To the best of our knowledge, this is the first report of successful treatment of LPP with a PRP regimen.

Keywords: alopecia; cicatricial alopecia; lichen planopillaris; local therapy; platelet-rich plasma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Lichen Planus / pathology
  • Lichen Planus / therapy*
  • Platelet-Rich Plasma*