Genetic variations (Arg5Pro and Leu6Pro) modulate the structure and activity of GPX1 and genetic risk for vitiligo

Exp Dermatol. 2016 Aug;25(8):654-7. doi: 10.1111/exd.13007. Epub 2016 May 19.
No abstract available

Keywords: glutathione peroxidase; lipid peroxidation; molecular dynamics simulation; oxidative stress; vitiligo.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Substitution
  • Case-Control Studies
  • Erythrocytes / enzymology
  • Female
  • Genetic Association Studies
  • Genetic Predisposition to Disease
  • Glutathione Peroxidase / genetics*
  • Humans
  • Linkage Disequilibrium
  • Lipid Peroxidation
  • Male
  • Molecular Dynamics Simulation
  • Vitiligo / genetics*

Substances

  • glutathione peroxidase GPX1
  • Glutathione Peroxidase