Deep brain stimulation and development of a high-grade glioma: incidental or causal association?

Acta Neurochir (Wien). 2016 May;158(5):915-7. doi: 10.1007/s00701-016-2773-9. Epub 2016 Mar 18.


We report the case of a patient in whom 8.8 years following the implantation of a bilateral deep brain stimulation (DBS) into the Vim, a high-grade glioma was diagnosed in close proximity to the two electrode leads. A possible relationship between the permanent DBS and the development of the brain tumour is discussed.

Keywords: Brain tumour; DBS; Glioma.

Publication types

  • Case Reports

MeSH terms

  • Brain Neoplasms / etiology*
  • Deep Brain Stimulation / adverse effects*
  • Electrodes / adverse effects
  • Glioma / etiology*
  • Humans
  • Male
  • Middle Aged