Advances in the prevention, management, and treatment of community-acquired pneumonia

F1000Res. 2016 Mar 8:5:F1000 Faculty Rev-300. doi: 10.12688/f1000research.7657.1. eCollection 2016.

Abstract

Community-acquired pneumonia (CAP) is the infectious disease with the highest number of deaths worldwide. Nevertheless, its importance is often underestimated. Large cohorts of patients with CAP have been established worldwide and improved our knowledge about CAP by far. Therefore, current guidelines are much more evidence-based than ever before. This article discusses recent major studies and concepts on CAP such as the role of biomarkers, appropriate risk stratification to identify patients in need of hospitalisation or intensive care, appropriate empiric antibiotic therapy (including the impact of macrolide combination therapy and antibiotic stewardship), and CAP prevention with novel influenza and pneumococcal vaccines.

Keywords: CAP; Streptococcus pneumoniae; community-acquired pneumonia; pulmonary infection.

Publication types

  • Review

Grants and funding

MP was supported by a grant from the German Ministry of Education and Research (grant number 01KI1204).