Carbon monoxide poisoning and pulmonary injury from the mixture of formic and sulfuric acids

Clin Toxicol (Phila). 2016 Jun;54(5):450-3. doi: 10.3109/15563650.2016.1157723. Epub 2016 Mar 21.

Abstract

Context: The inhalation of carbon monoxide produced by the incomplete combustion of carbon remains a popular method of suicide. A much less common method of producing carbon monoxide for suicide is by mixing formic and sulfuric acids.

Case details: We describe a patient who attempted suicide by mixing formic and sulfuric acids. He presented with a depressed level of consciousness, chemical burns of his airway and skin, and respiratory distress. He was found to have a metabolic acidosis, a carboxyhemoglobin of 36.8%, hyperkalemia, and rhabdomyolysis. His hospital course was notable for copious pulmonary secretions and hypoxia, but he ultimately recovered with supportive care.

Discussion: The case highlights the potential toxicity, particularly from inhaled carbon monoxide and formic acid, with this method of suicide.

Keywords: Carbon monoxide; carboxyhemoglobin; chemical pneumonitis; rescuer; suicide.

Publication types

  • Case Reports

MeSH terms

  • Administration, Inhalation
  • Adult
  • Burns, Chemical / diagnosis
  • Carbon Monoxide Poisoning / complications
  • Carbon Monoxide Poisoning / diagnosis*
  • Carboxyhemoglobin / metabolism
  • Formates / poisoning*
  • Humans
  • Hyperkalemia / chemically induced
  • Lung Injury / chemically induced*
  • Male
  • Rhabdomyolysis / chemically induced
  • Suicide, Attempted*
  • Sulfuric Acids / poisoning*

Substances

  • Formates
  • Sulfuric Acids
  • formic acid
  • Carboxyhemoglobin