The study on clinical value of the detection about serum and Unconjugated Bilirubin in diagnosis of neonatal jaundice

Pak J Pharm Sci. 2016 Jan;29(1 Suppl):339-41.

Abstract

In this paper, the clinical value of the detection about serum and unconjugated bilirubin (UCB) in neonatal jaundice was studied to found an effective and rapid method for diagnose of neonatal jaundice. ALB (Serum Albumin), total serum bilirubin (TSB) and UCB were detected by ELISA method among the 100 cases with neonatal jaundice selected for the study. The values of ALB, UCB and TSB in moderate jaundice patients were (42.83±3.87) g/L, (287.35±44.38) μm/L, (304.16±43.40) μm/L, respectively; as for the severe jaundice patients, the values were (38.41±4.82) g/L, (354.38±48.75) μm/L, (375.20±47.51) μm/L. The results showed significant differences with the p< 0.05 between moderate and severe jaundice patients. The level of ALB, UCB, TSB in hemolytic jaundice, obstructive jaundice and jaundice caused by other infections also had significant differences, and the difference was statistically significant (p<0.05). The detection of ALB and UCB provides a useful method for the diagnosis and assessment of neonatal jaundice.

MeSH terms

  • Bilirubin / blood*
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Humans
  • Infant, Newborn
  • Jaundice / blood
  • Jaundice / diagnosis
  • Jaundice, Neonatal / blood
  • Jaundice, Neonatal / diagnosis*
  • Jaundice, Neonatal / etiology
  • Jaundice, Obstructive / blood
  • Jaundice, Obstructive / diagnosis
  • Male
  • Predictive Value of Tests
  • Serum Albumin / analysis

Substances

  • Serum Albumin
  • Bilirubin