Post-stroke dysphagia: A review and design considerations for future trials

Int J Stroke. 2016 Jun;11(4):399-411. doi: 10.1177/1747493016639057. Epub 2016 Mar 22.


Post-stroke dysphagia (a difficulty in swallowing after a stroke) is a common and expensive complication of acute stroke and is associated with increased mortality, morbidity, and institutionalization due in part to aspiration, pneumonia, and malnutrition. Although most patients recover swallowing spontaneously, a significant minority still have dysphagia at six months. Although multiple advances have been made in the hyperacute treatment of stroke and secondary prevention, the management of dysphagia post-stroke remains a neglected area of research, and its optimal management, including diagnosis, investigation and treatment, have still to be defined.

Keywords: Stroke; aspiration; design; dysphagia; pneumonia; randomized controlled trial; rehabilitation; treatment.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Deglutition Disorders / diagnosis*
  • Deglutition Disorders / etiology
  • Deglutition Disorders / prevention & control
  • Deglutition Disorders / therapy*
  • Humans
  • Randomized Controlled Trials as Topic / methods
  • Research Design
  • Stroke / complications*
  • Stroke / diagnosis
  • Stroke / therapy