Pain in Times of Stress

Malays J Med Sci. 2015 Dec;22(Spec Issue):52-61.


Stress modulates pain perception, resulting in either stress-induced analgesia or stress-induced hyperalgesia, as reported in both animal and human studies. The responses to stress include neural, endocrine, and behavioural changes, and built-in coping strategies are in place to address stressors. Peculiar to humans are additional factors that modulate pain that are experienced in times of stress, notably psychological factors that potentially influence the directionality of pain perception.

Keywords: analgesia; hyperalgesia; neuroimaging; pain; stress.