Comparison of oropharyngeal leak pressure and clinical performance of LMA ProSeal™ and i-gel® in adults: Meta-analysis and systematic review

J Int Med Res. 2016 Jun;44(3):405-18. doi: 10.1177/0300060515607386. Epub 2016 Mar 23.


Background: A meta-analysis and systematic review of randomized controlled trials to compare the oropharyngeal leak pressure (OLP) and clinical performance of LMA ProSeal™ (Teleflex® Inc., Wayne, PA, USA) and i-gel® (Intersurgical Ltd, Wokingham, UK) in adults undergoing general anesthesia.

Methods: Searches of MEDLINE®, EMBASE®, CENTRAL, KoreaMed and Google Scholar® were performed. The primary objective was to compare OLP; secondary objectives included comparison of clinical performance and complications.

Results: Fourteen RCTs were included. OLP was significantly higher with LMA ProSeal™ than with i-gel® (mean difference [MD] -2.95 cmH2O; 95% confidence interval [CI] -4.30, -1.60). The i-gel® had shorter device insertion time (MD -3.01 s; 95% CI -5.80, -0.21), and lower incidences of blood on device after removal (risk ratio [RR] 0.32; 95% CI 0.18, 0.56) and sore throat (RR 0.56; 95% CI 0.35, 0.89) than LMA ProSeal™.

Conclusion: LMA ProSeal™ provides superior airway sealing compared to i-gel®.

Keywords: Airway sealing; equipment; i-gel®; laryngeal mask airway proseal; leak; meta-analysis.

Publication types

  • Comparative Study
  • Meta-Analysis
  • Review
  • Systematic Review

MeSH terms

  • Adult
  • Device Removal
  • Humans
  • Laryngeal Masks* / adverse effects
  • Pressure*
  • Publication Bias
  • Randomized Controlled Trials as Topic